Some cells age and retire — but instead of quietly disappearing, they hang around, useless and noisy.
These are senescent cells, also known as zombie cells.
They don’t divide, don’t die, and worst of all — they release a toxic “soup” called SASP (senescence-associated secretory phenotype).
At first, SASP can help repair wounds, but when zombie cells pile up, SASP turns harmful:
⚠️ In joints, it breaks down cartilage (arthritis).
⚠️ In blood vessels, it worsens plaque (heart disease).
⚠️ In fat and muscle, it fuels insulin resistance (diabetes).
⚠️ In skin, it destroys collagen (wrinkles).
⚠️ In the brain, it drives inflammation (Alzheimer’s).
If too many zombie cells build up, it’s like having angry neighbours shouting all day, stressing the whole neighbourhood (your body).
How AmCELL Evicts the Troublemakers:
✅ Quercetin is the bold hero — a senolytic, meaning it clears out zombie cells by switching off the signals that keep them alive, helping them self-destruct.
✅ Rutin is the calm negotiator — a senomorphic, meaning it doesn’t kill the cells, but silences their toxic SASP messages so they stop spreading damage.
✅ Cyanidin 3-O-Galactoside (C3G) adds a clever trick — boosting the cell’s recycling system (autophagy) to clean up damaged parts and restore balance.
This senolytic + senomorphic combo is rare — and AmCELL delivers both, helping your body stay cleaner, calmer, and younger from the inside out.
🔍 Coming up: What happens when your repair crew gets tired?
In Part 10, discover how AmCELL reawakens your stem cells — your body’s secret source of renewal.
References:
Hickson, L. J., Prata, L. G. L., Bobart, S. A., Evans, T. K., Giorgadze, N., Hashmi, S. K., ... & Kirkland, J. L. (2019). Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease. EBioMedicine, 47, 446-456.
Liang, Z., Liang, H., Guo, Y., & Yang, D. (2021). Cyanidin 3-O-galactoside: A natural compound with multiple health benefits. International journal of molecular sciences, 22(5), 2261.
Liu, H., Xu, Q., Wufuer, H., Li, Z., Sun, R., Jiang, Z., ... & Sun, Y. (2024). Rutin is a potent senomorphic agent to target senescent cells and can improve chemotherapeutic efficacy. Aging Cell, 23(1), e13921.nutrition, 63(28), 9163-9186.